A buen entendedor pocas palabras este Script se puede adaptar para que se aplique a usuarios o maquinas y ejecuta una aplicación sobre estos. reemplazar lo que esta entre comillas por shutdown y parámetros.

txtshutdown = "shutdown -r"

On Error Resume Next

Const ADS_SCOPE_SUBTREE = 2

Set objConnection = CreateObject("ADODB.Connection")
Set objCommand = CreateObject("ADODB.Command")
objConnection.Provider = "ADsDSOObject"
objConnection.Open "Active Directory Provider"

Set objCommand.ActiveConnection = objConnection
objCommand.CommandText = "Select Name, Location from ‘LDAP://OU=Centura,OU=contenedor,OU=Computadores,DC=contoso,DC=CL’ Where objectClass=’computer’"
objCommand.Properties("Page Size") = 1000
objCommand.Properties("Searchscope") = ADS_SCOPE_SUBTREE
Set objRecordSet = objCommand.Execute
objRecordSet.MoveFirst

Do Until objRecordSet.EOF
   ‘Wscript.Echo "Computer Name: " & objRecordSet.Fields("Name").Value
   ‘Wscript.Echo "Location: " & objRecordSet.Fields("Location").Value
   txtPCName = objRecordSet.Fields("Name").Value
   txtshutdown = "shutdown -r"
   set objShell = CreateObject("WScript.Shell")
   objShell.Run txtShutdown
   objRecordSet.MoveNext
Loop